Communication mechanisms exist inside our cells to regulate gene expression and function. In cells, communication between a gene and sequences that regulate the gene occurs through physical contact. These physical contacts between regulatory element enhancers and the gene promoters may activate gene expression. Our goal is to understand how this communication occurs within the nucleus. In particular, we leverage 3D genome mapping technologies to capture the dynamic chromatin interactions and study gene regulation in the context of developmental biology. Algorithms on graphs allow us to interpret these data generated from high-throughput sequencing assays.
How did you end up where you are today?
I studied electrical engineering, hoping to advance the field of information and coding theory. Instead, I aim to understand the communication mechanisms governing gene transcription.
What makes you excited about your data science and AI research?
Interpreting biological data is often a creative process. I enjoy browsing through the data, connecting pieces, and finding patterns.