This project explores how some proteins are better at evolving than others and asks whether this adaptability—or evolvability—can be intentionally built into or tuned out of newly designed proteins. By using AI tools trained on naturally evolved proteins, our team maps how mutations affect protein function and adaptability, focusing first on fluorescent proteins that are easy to mutate and test. The goal is to improve protein design methods so that scientists can build molecules that are not just functional today, but capable (or not) of adapting to future challenges.