I received my second PhD in Computer Science (with a focus on distributed systems and software engineering) from Virginia Tech USA in 2020, and the first PhD (with a focus on wireless networking and mobile computing) from Beijing University of Posts and Telecommunications China in 2015. I received the Best Paper Award from IEEE International Conference on Edge Computing in 2019. My ongoing research projects include measuring the data quality of web services and using federated learning to improve indoor localization accuracy.
Dr. Kochunas’s research focus is on the next generation of numerical methods and parallel algorithms for high fidelity computational reactor physics and how to leverage these capabilities to develop digital twins. His group’s areas of expertise include neutron transport, nuclide transmutation, multi-physics, parallel programming, and HPC architectures. The Nuclear Reactor Analysis and Methods (NURAM) group is also developing techniques that integrate data-driven methods with conventional approaches in numerical analysis to produce “hybrid models” for accurate, real-time modeling applications. This is embodied by his recent efforts to combine high-fidelity simulation results simulation models in virtual reality through the Virtual Ford Nuclear Reactor.
My lab researches how the human brain processes social and affective information and how these processes are affected in psychiatric disorders, especially schizophrenia and bipolar disorder. We use behavioral, electrophysiological (EEG), neuroimaging (functional MRI), eye tracking, brain stimulation (TMS, tACS), and computational methods in our studies. One main focus of our work is building and validating computational models based on intensive, high-dimensional subject-level behavior and brain data to explain clinical phenomena, parse mechanisms, and predict patient outcome. The goal is to improve diagnostic and prognostic assessment, and to develop personalized treatments.
Uncertainty quantification and decision making are increasingly demanded with the development of future technology in engineering and transportation systems. Among the uncertainty quantification problems, Dr. Wenbo Sun is particularly interested in statistical modelling of engineering system responses with considering the high dimensionality and complicated correlation structure, as well as quantifying the uncertainty from a variety of sources simultaneously, such as the inexactness of large-scale computer experiments, process variations, and measurement noises. He is also interested in data-driven decision making that is robust to the uncertainty. Specifically, he delivers methodologies for anomaly detection and system design optimization, which can be applied to manufacturing process monitoring, distracted driving detection, out-of-distribution object identification, vehicle safety design optimization, etc.
The Ahmed lab studies behavioral neural circuits and attempts to repair them when they go awry in neurological disorders. Working with patients and with transgenic rodent models, we focus on how space, time and speed are encoded by the spatial navigation and memory circuits of the brain. We also focus on how these same circuits go wrong in Alzheimer’s disease, Parkinson’s disease and epilepsy. Our research involves the collection of massive volumes of neural data. Within these terabytes of data, we work to identify and understand irregular activity patterns at the sub-millisecond level. This requires us to leverage high performance computing environments, and to design custom algorithmic and analytical signal processing solutions. As part of our research, we also discover new ways for the brain to encode information (how neurons encode sequences of space and time, for example) – and the algorithms utilized by these natural neural networks can have important implications for the design of more effective artificial neural networks.
I build data science tools to address challenges in medicine and clinical care. Specifically, I apply signal processing, image processing and machine learning techniques, including deep convolutional and recurrent neural networks and natural language processing, to aid diagnosis, prognosis and treatment of patients with acute and chronic conditions. In addition, I conduct research on novel approaches to represent clinical data and combine supervised and unsupervised methods to improve model performance and reduce the labeling burden. Another active area of my research is design, implementation and utilization of novel wearable devices for non-invasive patient monitoring in hospital and at home. This includes integration of the information that is measured by wearables with the data available in the electronic health records, including medical codes, waveforms and images, among others. Another area of my research involves linear, non-linear and discrete optimization and queuing theory to build new solutions for healthcare logistic planning, including stochastic approximation methods to model complex systems such as dispatch policies for emergency systems with multi-server dispatches, variable server load, multiple priority levels, etc.
My research focuses on the development of novel Magnetic Resonance Imaging (MRI) technology for imaging the heart. We focus in particular on quantitative imaging techniques, in which the signal intensity at each pixel in an image represents a measurement of an inherent property of a tissue. Much of our research is based on cardiac Magnetic Resonance Fingerprinting (MRF), which is a class of methods for simultaneously measuring multiple tissue properties from one rapid acquisition.
Our group is exploring novel ways to combine physics-based modeling of MRI scans with deep learning algorithms for several purposes. First, we are exploring the use of deep learning to design quantitative MRI scans with improved accuracy and precision. Second, we are developing deep learning approaches for image reconstruction that will allow us to reduce image noise, improve spatial resolution and volumetric coverage, and enable highly accelerated acquisitions to shorten scan times. Third, we are exploring ways of using artificial intelligence to derive physiological motion signals directly from MRI data to enable continuous scanning that is robust to cardiac and breathing motion. In general, we focus on algorithms that are either self-supervised or use training data generated in computer simulations, since the collection of large amounts of training data from human subjects is often impractical when designing novel imaging methods.
My reserach group–theNeurobionics Lab–has two chief goals. Firstly, we seek to answer fundamental questions about human locomotion through a deeper understanding of how limb mechanics are felt and regulated by the nervous system. These properties are important because they govern how people respond to disturbances during gait, such as unexpectedly stepping on an obstacle, or carefully walking over uneven terrain. Moreover, the ability to regulate these mechanics is drastically impaired following neurological injury. As a result, impaired individuals fall more frequently, fatigue faster, and have abnormal gait patterns that inhibit daily life. The more we understand about how the brain controls the body during locomotion, the better we can assess, track, and treat the changes that occur following neurological injury.
The second mission of the group is to develop technologies that address the deficits that arise from neuropathologies and amputation. We leverage biomimetic design and control approaches to develop novel wearable robotic systems. Our intent is to not only address the locomotor deficits of these individuals, but also enable them to exceed the performance of their able-bodied counterparts. Our approach is unique: the biomechanical science that we discover is used to develop a new class of assistive technology. Through interdisciplinary, bidirectional feedback between science and engineering, the Neurobionics Lab conducts innovative work that will eventually impact the lives of the disabled.
• Computational dynamics focused on nonlinear dynamics and finite elements (e.g., a new approach for forecasting bifurcations/tipping points in aeroelastic and ecological systems, new finite element methods for thin walled beams that leads to novel reduced order models).
• Modeling nonlinear phenomena and mechano-chemical processes in molecular motor dynamics, such as motor proteins, toward early detection of neurodegenerative diseases.
• Computational methods for robotics, manufacturing, modeling multi-body dynamics, developed methods for identifying limit cycle oscillations in large-dimensional (fluid) systems.
• Turbomachinery and aeroelasticity providing a better understanding of fundamental complex fluid dynamics and cutting-edge models for predicting, identifying and characterizing the response of blisks and flade systems through integrated experimental & computational approaches.
• Structural health monitoring & sensing providing increased sensibility / capabilities by the discovery, characterization and exploitation of sensitivity vector fields, smart system interrogation through nonlinear feedback excitation, nonlinear minimal rank perturbation and system augmentation, pattern recognition for attractors, damage detection using bifurcation morphing.