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Jeffrey Regier

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Jeffrey Regier received a PhD in statistics from UC Berkeley (2016) and joined the University of Michigan as an assistant professor. His research interests include graphical models, Bayesian inference, high-performance computing, deep learning, astronomy, and genomics.

Mark P Van Oyen

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Efficient, low regret contextual multi-armed bandit approaches for real time learning including Thompson sampling, UCB, and knowledge gradient descent. Integration of optimization and predictive analytics for determining the time to next measurement, which modality to use, and the optimal control of risk factors to manage chronic disease. Integration of soft voting ensemble classifiers and multiple models Kalman filters for disease state prediction, Real-time (online) contextual multi-armed bandits integrated with optimization of hospital bed type dynamic control decisions for reducing 30-day readmission rates in hospitals. Robustness in system optimization when the system model is uncertain with emphasis on quantile regression forests, sample average approximation, robust optimization and distributionally robust optimization. Health care delivery systems models with prediction and control for inpatient and outpatient. Work has been done on Emergency Department redesign for improved patient flow; Capacity management and planning and scheduling for outpatient care, including integrated services networks; admission control with machine learning to ICUs, stepdown, and regular care units Surgical planning and scheduling for access delay control; Planning and scheduling for Clinical Research Units.

Machine learning, system modeling, and stochastic control can be used to slow the rate of glaucoma progression based on treatment aggressiveness options selected jointly with the patient.

Aaron A. King

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The long temporal and large spatial scales of ecological systems make controlled experimentation difficult and the amassing of informative data challenging and expensive. The resulting sparsity and noise are major impediments to scientific progress in ecology, which therefore depends on efficient use of data. In this context, it has in recent years been recognized that the onetime playthings of theoretical ecologists, mathematical models of ecological processes, are no longer exclusively the stuff of thought experiments, but have great utility in the context of causal inference. Specifically, because they embody scientific questions about ecological processes in sharpest form—making precise, quantitative, testable predictions—the rigorous confrontation of process-based models with data accelerates the development of ecological understanding. This is the central premise of my research program and the common thread of the work that goes on in my laboratory.

Harm Derksen

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Current research includes a project funded by Toyota that uses Markov Models and Machine Learning to predict heart arrhythmia, an NSF-funded project to detect Acute Respiratory Distress Syndrome (ARDS) from x-ray images and projects using tensor analysis on health care data (funded by the Department of Defense and National Science Foundation).

Yongsheng Bai

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Dr. Bai’s research interests lie in development and refinement of bioinformatics algorithms/software and databases on next-generation sequencing (NGS data), development of statistical model for solving biological problems, bioinformatics analysis of clinical data, as well as other topics including, but not limited to, uncovering disease genes and variants using informatics approaches, computational analysis of cis-regulation and comparative motif finding, large-scale genome annotation, comparative “omics”, and evolutionary genomics.

Xun Huan

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Prof. Huan’s research broadly revolves around uncertainty quantification, data-driven modeling, and numerical optimization. He focuses on methods to bridge together models and data: e.g., optimal experimental design, Bayesian statistical inference, uncertainty propagation in high-dimensional settings, and algorithms that are robust to model misspecification. He seeks to develop efficient numerical methods that integrate computationally-intensive models with big data, and combine uncertainty quantification with machine learning to enable robust and reliable prediction, design, and decision-making.

Optimal experimental design seeks to identify experiments that produce the most valuable data. For example, when designing a combustion experiment to learn chemical kinetic parameters, design condition A maximizes the expected information gain. When Bayesian inference is performed on data from this experiment, we indeed obtain “tighter” posteriors (with less uncertainty) compared to those obtained from suboptimal design conditions B and C.

Neda Masoud

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The future of transportation lies at the intersection of two emerging trends, namely, the sharing economy and connected and automated vehicle technology. Our research group investigates the impact of these two major trends on the future of mobility, quantifying the benefits and identifying the challenges of integrating these technologies into our current systems.

Our research on shared-use mobility systems focuses on peer-to-peer (P2P) ridesharing and multi-modal transportation. We provide: (i) operational tools and decision support systems for shared-use mobility in legacy as well as connected and automated transportation systems. This line of research focuses on system design as well as routing, scheduling, and pricing mechanisms to serve on-demand transportation requests; (ii) insights for regulators and policy makers on mobility benefits of multi-modal transportation; (ii) planning tools that would allow for informed regulations of sharing economy.

In another line of research we investigate challenges faced by the connected automated vehicle technology before mass adoption of this technology can occur. Our research mainly focuses on (i) transition of control authority between the human driver and the autonomous entity in semi-autonomous (level 3 SAE autonomy) vehicles; (ii) incorporating network-level information supplied by connected vehicle technology into traditional trajectory planning; (iii) improving vehicle localization by taking advantage of opportunities provided by connected vehicles; and (iv) cybersecurity challenges in connected and automated systems. We seek to quantify the mobility and safety implications of this disruptive technology, and provide insights that can allow for informed regulations.

Tim Cernak

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Tim Cernak, PhD, is Assistant Professor of Medicinal Chemistry with secondary appointments in Chemistry and the Chemical Biology Program at the University of Michigan, Ann Arbor.

The functional and biological properties of a small molecule are encoded within its structure so synthetic strategies that access diverse structures are paramount to the invention of novel functional molecules such as biological probes, materials or pharmaceuticals. The Cernak Lab studies the interface of chemical synthesis and computer science to understand the relationship of structure, properties and reactions. We aim to use algorithms, robotics and big data to invent new chemical reactions, synthetic routes to natural products, and small molecule probes to answer questions in basic biology. Researchers in the group learn high-throughput chemical and biochemical experimentation, basic coding, and modern synthetic techniques. By studying the relationship of chemical synthesis to functional properties, we pursue the opportunity to positively impact human health.

Brian P. McCall

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My interests are in the areas of labor economics, program evaluation, and the economics of education. Currently my research focuses on college student debt accumulation and the subsequent risk of default, the effect of tuition subsidies on college attendance, the influence of family wealth on college attendance and completion, the effect of financial aid packages on college attendance, completion and subsequent labor market earnings, the influence of education on job displacement and subsequent earnings, the impact of unemployment insurance rules on unemployment durations and re-employment wages, and the determinants and consequences of repeat use of the unemployment insurance system.