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Veera Baladandayuthapani

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Dr. Veera Baladandayuthapani is currently a Professor in the Department of Biostatistics at University of Michigan (UM), where he is also the Associate Director of the Center for Cancer Biostatistics. He joined UM in Fall 2018 after spending 13 years in the Department of Biostatistics at University of Texas MD Anderson Cancer Center, Houston, Texas, where was a Professor and Institute Faculty Scholar and held adjunct appointments at Rice University, Texas A&M University and UT School of Public Health. His research interests are mainly in high-dimensional data modeling and Bayesian inference. This includes functional data analyses, Bayesian graphical models, Bayesian semi-/non-parametric models and Bayesian machine learning. These methods are motivated by large and complex datasets (a.k.a. Big Data) such as high-throughput genomics, epigenomics, transcriptomics and proteomics as well as high-resolution neuro- and cancer- imaging. His work has been published in top statistical/biostatistical/bioinformatics and biomedical/oncology journals. He has also co-authored a book on Bayesian analysis of gene expression data. He currently holds multiple PI-level grants from NIH and NSF to develop innovative and advanced biostatistical and bioinformatics methods for big datasets in oncology. He has also served as the Director of the Biostatistics and Bioinformatics Cores for the Specialized Programs of Research Excellence (SPOREs) in Multiple Myeloma and Lung Cancer and Biostatistics&Bioinformatics platform leader for the Myeloma and Melanoma Moonshot Programs at MD Anderson. He is a fellow of the American Statistical Association and an elected member of the International Statistical Institute. He currently serves as an Associate Editor for Journal of American Statistical Association, Biometrics and Sankhya.

 

An example of horizontal (across cancers) and vertical (across multiple molecular platforms) data integration. Image from Ha et al (Nature Scientific Reports, 2018; https://www.nature.com/articles/s41598-018-32682-x)

Kathleen M Bergen

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Kathleen M Bergen, PhD, is Associate Research Scientist in the School for Environment and Sustainability at the University of Michigan, Ann Arbor. Dr. Bergen currently has interim administrative oversight of the SEAS Environmental Spatial Analysis Laboratory (ESALab) and is interim Director of the campus-wide Graduate Certificate Program in Spatial Analysis.

Prof. Bergen works in the areas of human dimensions of environmental change; remote sensing, GIS and biodiversity informatics; and environmental health and informatics. Her focus is on combining field and geospatial data and methods to study the pattern and process of ecological systems, biodiversity and health. She also strives to build bridges between science and social science to understand the implications of human actions on the social and natural systems of which we are a part. She teaches courses in Remote Sensing and Geographic Information Systems. Formerly she served as a founding member of the UM LIbrary’s MIRLYN implementation team, directed the University Map Collection, and set up the M-Link reference information network.

Brenda Gillespie

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Brenda Gillespie, PhD, is Associate Director in Consulting for Statistics, Computing and Analytics Research (CSCAR) with a secondary appointment as Associate Research Professor in the department of Biostatistics in the School of Public Health at the University of Michigan, Ann Arbor. She provides statistical collaboration and support for numerous research projects at the University of Michigan. She teaches Biostatistics courses as well as CSCAR short courses in survival analysis, regression analysis, sample size calculation, generalized linear models, meta-analysis, and statistical ethics. Her major areas of expertise are clinical trials and survival analysis.

Prof. Gillespie’s research interests are in the area of censored data and clinical trials. One research interest concerns the application of categorical regression models to the case of censored survival data. This technique is useful in modeling the hazard function (instead of treating it as a nuisance parameter, as in Cox proportional hazards regression), or in the situation where time-related interactions (i.e., non-proportional hazards) are present. An investigation comparing various categorical modeling strategies is currently in progress.

Another area of interest is the analysis of cross-over trials with censored data. Brenda has developed (with M. Feingold) a set of nonparametric methods for testing and estimation in this setting. Our methods out-perform previous methods in most cases.

Brian Min

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Brian Min, PhD, is Associate Professor of Political Science in the College of Literature, Science, and the Arts at the University of Michigan, Ann Arbor. Prof. Min holds secondary appointments as Research Associate Professor in the Center for Political Studies and the Institute for Social Research.

Prof. Min studies the political economy of development with an emphasis on distributive politics, public goods provision, and energy politics. His research uses high-resolution satellite imagery to study the distribution of electricity across and within the developing world. He has collaborated closely with the World Bank using satellite technologies and statistical algorithms to monitor electricity access in India and Africa, including the creation of a web platform to visualize twenty years of change in light output for every village in India (http://nightlights.io).

 

min-nightlights

Kai S. Cortina

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Kai S. Cortina, PhD, is Professor of Psychology in the College of Literature, Science, and the Arts at the University of Michigan, Ann Arbor.

Prof. Cortina’s major research revolves around the understanding of children’s and adolescents’ pathways into adulthood and the role of the educational system in this process. The academic and psycho-social development is analyzed from a life-span perspective exclusively analyzing longitudinal data over longer periods of time (e.g., from middle school to young adulthood). The hierarchical structure of the school system (student/classroom/school/district/state/nations) requires the use of statistical tools that can handle these kind of nested data.

 

Jason Corso

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The Corso group’s main research thrust is high-level computer vision and its relationship to human language, robotics and data science. They primarily focus on problems in video understanding such as video segmentation, activity recognition, and video-to-text; methodology, models leveraging cross-model cues to learn structured embeddings from large-scale data sources as well as graphical models emphasizing structured prediction over large-scale data sources are their emphasis. From biomedicine to recreational video, imaging data is ubiquitous. Yet, imaging scientists and intelligence analysts are without an adequate language and set of tools to fully tap the information-rich image and video. His group works to provide such a language.  His long-term goal is a comprehensive and robust methodology of automatically mining, quantifying, and generalizing information in large sets of projective and volumetric images and video to facilitate intelligent computational and robotic agents that can natural interact with humans and within the natural world.

Relating visual content to natural language requires models at multiple scales and emphases; here we model low-level visual content, high-level ontological information, and these two are glued together with an adaptive graphical structure at the mid-level.

Relating visual content to natural language requires models at multiple scales and emphases; here we model low-level visual content, high-level ontological information, and these two are glued together with an adaptive graphical structure at the mid-level.

Timothy Pletcher

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My current research focus is on modeling and simulating the value and benefits of various data sharing and policy trade offs. Typically these utilize system dynamics methodologies and tools.

I also have considerable experience across multiple industries with developing processes to enable industry and faculty to identify and solve data science problems using SAS tools.

Omid Dehzangi

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Omid Dehzangi, PhD, is Assistant Professor of Computer and Information Science, College of Engineering and Computer Science, at the University of Michigan, Dearborn.

Wearable health technology is drawing significant attention for good reasons. The pervasive nature of such systems providing ubiquitous access to the continuous personalized data will transform the way people interact with each other and their environment. The resulting information extracted from these systems will enable emerging applications in healthcare, wellness, emergency response, fitness monitoring, elderly care support, long-term preventive chronic care, assistive care, smart environments, sports, gaming, and entertainment which create many new research opportunities and transform researches from various disciplines into data science which is the methodological terminology for data collection, data management, data analysis, and data visualization. Despite the ground-breaking potentials, there are a number of interesting challenges in order to design and develop wearable medical embedded systems. Due to limited available resources in wearable processing architectures, power-efficiency is demanded to allow unobtrusive and long-term operation of the hardware. Also, the data-intensive nature of continuous health monitoring requires efficient signal processing and data analytic algorithms for real-time, scalable, reliable, accurate, and secure extraction of relevant information from an overwhelmingly large amount of data. Therefore, extensive research in their design, development, and assessment is necessary. Embedded Processing Platform Design The majority of my work concentrates on designing wearable embedded processing platforms in order to shift the conventional paradigms from hospital-centric healthcare with episodic and reactive focus on diseases to patient-centric and home-based healthcare as an alternative segment which demands outstanding specialized design in terms of hardware design, software development, signal processing and uncertainty reduction, data analysis, predictive modeling and information extraction. The objective is to reduce the costs and improve the effectiveness of healthcare by proactive early monitoring, diagnosis, and treatment of diseases (i.e. preventive) as shown in Figure 1.

Figure 1. Embedded processing platform in healthcare

Issam El Naqa

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Our lab’s research interests are in the areas of oncology bioinformatics, multimodality image analysis, and treatment outcome modeling. We operate at the interface of physics, biology, and engineering with the primary motivation to design and develop novel approaches to unravel cancer patients’ response to chemoradiotherapy treatment by integrating physical, biological, and imaging information into advanced mathematical models using combined top-bottom and bottom-top approaches that apply techniques of machine learning and complex systems analysis to first principles and evaluating their performance in clinical and preclinical data. These models could be then used to personalize cancer patients’ chemoradiotherapy treatment based on predicted benefit/risk and help understand the underlying biological response to disease. These research interests are divided into the following themes:

  • Bioinformatics: design and develop large-scale datamining methods and software tools to identify robust biomarkers (-omics) of chemoradiotherapy treatment outcomes from clinical and preclinical data.
  • Multimodality image-guided targeting and adaptive radiotherapy: design and develop hardware tools and software algorithms for multimodality image analysis and understanding, feature extraction for outcome prediction (radiomics), real-time treatment optimization and targeting.
  • Radiobiology: design and develop predictive models of tumor and normal tissue response to radiotherapy. Investigate the application of these methods to develop therapeutic interventions for protection of normal tissue toxicities.