Dr. Likosky is a Professor, Head of the Section of Health Services Research and Quality in the Department of Cardiac Surgery at Michigan Medicine and faculty member at the Center for Healthcare Outcomes and Policy. Dr. Likosky’s work currently focuses on leveraging: (i) mobile health technology to identify objective and scalable measures for mitigating post-surgical morbidities, and (ii) computer vision to identify objective and scalable measures of important intraoperative technical skills and non-technical practices.
We are interested in resolving outstanding fundamental scientific problems that impede the computational materials design process. Our group uses high-throughput density functional theory, applied thermodynamics, and materials informatics to deepen our fundamental understanding of synthesis-structure-property relationships, while exploring new chemical spaces for functional technological materials. These research interests are driven by the practical goal of the U.S. Materials Genome Initiative to accelerate materials discovery, but whose resolution requires basic fundamental research in synthesis science, inorganic chemistry, and materials thermodynamics.
We have developed and tested machine learning approaches to integrate quantitative markers for diagnosis and assessment of progression of TMJ OA, as well as extended the capabilities of 3D Slicer4 into web-based tools and disseminated open source image analysis tools. Our aims use data processing and in-depth analytics combined with learning using privileged information, integrated feature selection, and testing the performance of longitudinal risk predictors. Our long term goals are to improve diagnosis and risk prediction of TemporoMandibular Osteoarthritis in future multicenter studies.
The Spectrum of Data Science for Diagnosis of Osteoarthritis of the Temporomandibular Joint
As a board-certified ophthalmologist and glaucoma specialist, I have more than 15 years of clinical experience caring for patients with different types and complexities of glaucoma. In addition to my clinical experience, as a health services researcher, I have developed experience and expertise in several disciplines including performing analyses using large health care claims databases to study utilization and outcomes of patients with ocular diseases, racial and other disparities in eye care, associations between systemic conditions or medication use and ocular diseases. I have learned the nuances of various data sources and ways to maximize our use of these data sources to answer important and timely questions. Leveraging my background in HSR with new skills in bioinformatics and precision medicine, over the past 2-3 years I have been developing and growing the Sight Outcomes Research Collaborative (SOURCE) repository, a powerful tool that researchers can tap into to study patients with ocular diseases. My team and I have spent countless hours devising ways of extracting electronic health record data from Clarity, cleaning and de-identifying the data, and making it linkable to ocular diagnostic test data (OCT, HVF, biometry) and non-clinical data. Now that we have successfully developed such a resource here at Kellogg, I am now collaborating with colleagues at > 2 dozen academic ophthalmology departments across the country to assist them with extracting their data in the same format and sending it to Kellogg so that we can pool the data and make it accessible to researchers at all of the participating centers for research and quality improvement studies. I am also actively exploring ways to integrate data from SOURCE into deep learning and artificial intelligence algorithms, making use of SOURCE data for genotype-phenotype association studies and development of polygenic risk scores for common ocular diseases, capturing patient-reported outcome data for the majority of eye care recipients, enhancing visualization of the data on easy-to-access dashboards to aid in quality improvement initiatives, and making use of the data to enhance quality of care, safety, efficiency of care delivery, and to improve clinical operations. .
Dr. Douville is a critical care anesthesiologist with an investigative background in bioinformatics and perioperative outcomes research. He studies techniques for utilizing health care data, including genotype, to deliver personalized medicine in the perioperative period and intensive care unit. His research background has focused on ways technology can assist health care delivery to improve patient outcomes. This began designing microfluidic chips capable of recreating fluid mechanics of atelectatic alveoli and monitoring the resulting barrier breakdown real-time. His interest in bioinformatics was sparked when he observed how methodology designed for tissue engineering could be modified to the nano-scale to enable genomic analysis. Additionally, his engineering training provided the framework to apply data-driven modeling techniques, such as finite element analysis, to complex biological systems.
My research focuses on the causes, dynamics and outcomes of conflict, at the international and local levels. My methodological areas of interest include spatial statistics, mathematical/computational modeling and text analysis.
Map/time-series/network plot, showing the flow of information across battles in World War II. Z axis is time, X and Y axes are longitude and latitude, polygons are locations of battles, red lines are network edges linking battles involving the same combatants. Source: https://doi.org/10.1017/S0020818318000358
Jeffrey D. Morenoff is a professor of sociology, a research professor at the Institute for Social Research (ISR), and a professor of public policy at the Ford School. He is also director of the ISR Population Studies Center. Professor Morenoff’s research interests include neighborhood environments, inequality, crime and criminal justice, the social determinants of health, racial/ethnic/immigrant disparities in health and antisocial behavior, and methods for analyzing multilevel and spatial data.
I am a social epidemiologist with expertise in data collection, analysis, and translation. My research is focused on quantifying health inequities at the individual, community, and national level and examining how policy and social factors impact these inequities. My experience has spanned academic, clinical, and community settings, providing me with a unique perspective on the value and need for epidemiologic research and dissemination in multiple contexts. My current work focuses on the health equity impact of tobacco product use as part of the University of Michigan Tobacco Center of Regulatory Science, the Center for the Assessment of Tobacco Regulations (CAsToR). I am examining sociodemographic inequities in polytobacco use (the use of multiple tobacco products) across multiple nationally representative datasets. I am also an active member of CAsToR’s Data Analysis and Dissemination (DAD) Core. Additionally, I am collaborating with colleagues in Chicago to disseminate findings from a community-level probability survey of 10 Chicago communities, of which I served as Co-PI while working at a hospital system in Chicago. We continue to publish on the unique survey process, sharing our community-driven approach to conducting research and disseminating findings in partnership with surveyed communities.
Dr. Fleischer’s research focuses on how the broader socioeconomic and policy environments impact health disparities and the health of vulnerable populations, in the U.S. and around the world. Through this research, her group employs various analytic techniques to examine data at multiple levels (country-level, state-level, and neighborhood-level), emphasizing the role of structural influences on individual health. Her group applies advanced epidemiologic, statistical, and econometric methods to this research, including survey methodology, longitudinal data analysis, hierarchical modeling, causal inference, systems science, and difference-in-difference analysis. Dr. Fleischer leads two NCI-funded projects focused on the impact of tobacco control policies on health equity in the U.S.