The Ahmed lab studies behavioral neural circuits and attempts to repair them when they go awry in neurological disorders. Working with patients and with transgenic rodent models, we focus on how space, time and speed are encoded by the spatial navigation and memory circuits of the brain. We also focus on how these same circuits go wrong in Alzheimer’s disease, Parkinson’s disease and epilepsy. Our research involves the collection of massive volumes of neural data. Within these terabytes of data, we work to identify and understand irregular activity patterns at the sub-millisecond level. This requires us to leverage high performance computing environments, and to design custom algorithmic and analytical signal processing solutions. As part of our research, we also discover new ways for the brain to encode information (how neurons encode sequences of space and time, for example) – and the algorithms utilized by these natural neural networks can have important implications for the design of more effective artificial neural networks.
Prof. Huang is specialized in satellite remote sensing, atmospheric radiation, and climate modeling. Optimization, pattern analysis, and dimensional reduction are extensively used in his research for explaining observed spectrally resolved infrared spectra, estimating geophysical parameters from such hyperspectral observations, and deducing human influence on the climate in the presence of natural variability of the climate system. His group has also developed a deep-learning model to make a data-driven solar forecast model for use in the renewable energy sector.
My broad research interests are in multi-agent systems, computational economics and finance, and artificial intelligence. I apply techniques from algorithmic game theory, statistical machine learning, decision theory, etc. to a variety of problems at the intersection of the computational and social sciences. A major focus of my research has been the design and analysis of market-making algorithms for financial markets and, in particular, prediction markets — incentive-based mechanisms for aggregating data in the form of private beliefs about uncertain events (e.g. the outcome of an election) distributed among strategic agents. I use both analytical and simulation-based methods to investigate the impact of factors such as wealth, risk attitude, manipulative behavior, etc. on information aggregation in market ecosystems. Another line of work I am pursuing involves algorithms for allocating resources based on preference data collected from potential recipients, satisfying efficiency, fairness, and diversity criteria; my joint work on ethnicity quotas in Singapore public housing allocation deserves special mention in this vein. More recently, I have got involved in research on empirical game-theoretic analysis, a family of methods for building tractable models of complex, procedurally defined games from empirical/simulated payoff data and using them to reason about game outcomes.
• Computational dynamics focused on nonlinear dynamics and finite elements (e.g., a new approach for forecasting bifurcations/tipping points in aeroelastic and ecological systems, new finite element methods for thin walled beams that leads to novel reduced order models).
• Modeling nonlinear phenomena and mechano-chemical processes in molecular motor dynamics, such as motor proteins, toward early detection of neurodegenerative diseases.
• Computational methods for robotics, manufacturing, modeling multi-body dynamics, developed methods for identifying limit cycle oscillations in large-dimensional (fluid) systems.
• Turbomachinery and aeroelasticity providing a better understanding of fundamental complex fluid dynamics and cutting-edge models for predicting, identifying and characterizing the response of blisks and flade systems through integrated experimental & computational approaches.
• Structural health monitoring & sensing providing increased sensibility / capabilities by the discovery, characterization and exploitation of sensitivity vector fields, smart system interrogation through nonlinear feedback excitation, nonlinear minimal rank perturbation and system augmentation, pattern recognition for attractors, damage detection using bifurcation morphing.
Tayo Fabusuyi is an assistant research scientist in the Human Factors Group at UMTRI. His research interests are in Urban Systems and Operations Research, specifically designing and implementing initiatives that support sustainable and resilient communities with a focus on efficiency and equity issues. Drawing on both quantitative and qualitative data, his research develops and applies hard and soft Operations Research methods to urban systems issues in a manner that emphasizes theory driven solutions with demonstrated value-added. A central theme of his research activities is the use of demand side interventions, via information and pricing strategies in influencing the public’s travel behavior with the objective of achieving more beneficial societal outcomes. Informed by the proliferation of big data and the influence of transportation in the urban sphere, these research activities are categorized broadly into three overlapping and interdependent areas – intelligent transportation systems (ITS), emerging mobility services and urban futures. Before joining the research faculty at UMTRI, Dr. Fabusuyi was a Planning Economist at the African Development Bank and an adjunct Economics faculty member at Carnegie Mellon University, where he received his Ph.D. in Engineering and Public Policy.
My work lies in the learning, control, and design of autonomous systems with an emphasis on connected automated vehicles (CAVs). I have been committed to developing robust autonomous vehicles, augmented reality (AR) technology, and V2X systems at Mcity. The highlights include: (1) a robust self-driving algorithm/software stack enabling high-level CAVs; (2) a data-and-AI-driven sensor-level augmented reality (AR) system for efficient safe CAV tests. These systems have been deployed on the Mcity CAV fleet and Mcity testing track for daily operations. I am interested in using big naturalistic human-driving data to train motion planning and control algorithms of self-driving cars, so the automated cars could behave with better roadmanship and thus higher acceptance. I am also interested in data-driven low-uncertainty learning algorithms for object detection, tracking, and fusion, in order to build the perception system of safety-critical autonomous systems.
The Aguilar group is focused understanding transcriptional and epigenetic mechanisms of skeletal muscle stem cells in diverse contexts such as regeneration after injury and aging. We focus on this area because there are little to no therapies for skeletal muscle after injury or aging. We use various types of in-vivo and in-vitro models in combination with genomic assays and high-throughput sequencing to study these molecular mechanisms.
Dr. Arpan Kusari has joined UMTRI as an Assistant Research Scientist, a position where he will bring his cutting-edge industry experience. Dr. Kusari has spent five years at Ford Motor Company researching exclusively on making autonomous vehicles safe and viable, working collaboratively with researchers from MIT and University of Michigan to advance the state-of-the-art knowledge in autonomous vehicles. His research interest spans through the spheres of sensing and perception; and decision-making and control, in the domain of autonomous vehicles. In the sensing and perception realm, his interests lie in uncertainty quantification and fault tolerance of a generic sensor suite. Dr. Kusari is also interested in utilizing noise reduction methods for designing cost-effective low SNR (signal-to-noise ratio) LiDARS. In decision making and control, he is focused on creating a robust framework capable of handling the uncertainty stemming from other road users’ behavior. In that regard, Dr. Kusari is pursuing development of methods for increasing the efficiency and robustness of probabilistic formalisms such as reinforcement learning and evolutionary algorithms to safely navigate the dynamic environment. His doctoral research was in LiDAR mapping in the areas of sensor calibration, precise estimation of earthquake displacement and uncertainty quantification in the point cloud.
My methodological research focus on developing statistical methods for routinely collected healthcare databases such as electronic health records (EHR) and claims data. I aim to tackle the unique challenges that arise from the secondary use of real-world data for research purposes. Specifically, I develop novel causal inference methods and semiparametric efficiency theory that harness the full potential of EHR data to address comparative effectiveness and safety questions. I develop scalable and automated pipelines for curation and harmonization of EHR data across healthcare systems and coding systems.
Our research aims to address fundamental problems in both biomedical research and computer science by developing new tools tailored to rapidly emerging single-cell omic technologies. Broadly, we seek to understand what genes define the complement of cell types and cell states within healthy tissue, how cells differentiate to their final fates, and how dysregulation of genes within specific cell types contributes to human disease. As computational method developers, we seek to both employ and advance the methods of machine learning, particularly for unsupervised analysis of high-dimensional data. We have particular expertise in manifold learning, matrix factorization, and deep learning approaches.