Nicole Seiberlich

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My research involves developing novel data collection strategies and image reconstruction techniques for Magnetic Resonance Imaging. In order to accelerate data collection, we take advantage of features of MRI data, including sparsity, spatiotemporal correlations, and adherence to underlying physics; each of these properties can be leveraged to reduce the amount of data required to generate an image and thus speed up imaging time. We also seek to understand what image information is essential for radiologists in order to optimize MRI data collection and personalize the imaging protocol for each patient. We deploy machine learning algorithms and optimization techniques in each of these projects. In some of our work, we can generate the data that we need to train and test our algorithms using numerical simulations. In other portions, we seek to utilize clinical images, prospectively collected MRI data, or MRI protocol information in order to refine our techniques.

We seek to develop technologies like cardiac Magnetic Resonance Fingerprinting (cMRF), which can be used to efficiently collect multiple forms of information to distinguish healthy and diseased tissue using MRI. By using rapid methods like cMRF, quantitative data describing disease processes can be gathered quickly, enabling more and sicker patients can be assessed via MRI. These data, collected from many patients over time, can also be used to further refine MRI technologies for the assessment of specific diseases in a tailored, patient-specific manner.

Prasad R. Shankar

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I am an assistant professor of Radiology and an clinical researcher in the division of abdominal radiology. I am the departmental Associate Chair for Quality and Safety and chair of our departmental quality/safety research group, the Michigan Radiology Quality Collaborative. I have strong clinical and research interests in prostate cancer diagnosis and testing-related quality of life. I am actively engaged in research efforts to optimize precision imaging selection, through the help of big data.

Jeff Fessler

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My research group develops models and algorithms for large-scale inverse problems, especially image reconstruction for X-ray CT and MRI.  The models include those based on sparsity using dictionaries learned from large-scale data sets.  Developing efficient and accurate methods for dictionary learning is a recent focus.

For a summary of how model-based image reconstruction methods lead to improved image quality and/or lower X-ray doses, see: http://web.eecs.umich.edu/~fessler/re

To see how model-based image reconstruction methods lead to improved image quality and/or lower X-ray doses, see: http://web.eecs.umich.edu/~fessler/rehttp://web.eecs.umich.edu/~fessler/result/ct/