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Microbiology and Immunology

Denise Kirschner

My research for almost 30 years has focused on questions related to the immune response aspect of host-pathogen interactions in infectious diseases. My research has pioneered models of host-pathogen dynamics at multiple spatial and time scales and in multiple physiological compartments including lung, lymph nodes and blood. We were one of the first people to ...

David H. Sherman

My group is interested in the discovery and characterization of natural product molecules for pharmaceutical development. Our pipeline relating to data science begins with microbial genome sequencing, mining of natural product biosynthetic gene clusters, integration of LC-MS/MS, and biological activity data. A major challenge in the field of natural product sciences is to 3-dimensional structures ...

Thomas Schmidt

The current goal of our research is to learn enough about the physiology and ecology of microbes and microbial communities in the gut that we are able to engineer the gut microbiome to improve human health. The first target of our engineering is the production of butyrate – a common fermentation product of some gut ...

Patrick Schloss

The Schloss lab is broadly interested in beneficial and pathogenic host-microbiome interactions with the goal of improving our understanding of how the microbiome can be used to reach translational outcomes in the prevention, detection, and treatment of colorectal cancer, Crohn’s disease, and Clostridium difficile infection. To address these questions, we test traditional ecological theory in ...

Yongqun (Oliver) He

My laboratory data science research includes: (1) Ontology development. We have initiated and led the development of several community-based ontologies, including Vaccine Ontology (VO), Ontology of Adverse Events (OAE), Cell Line Ontology (CLO), Ontology of Genes and Genomes (OGG), and Interaction Network Ontology (INO). (2) Ontology tool development. We have developed many ontology software programs, ...

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Yongqun (Oliver) He

Professor of Microbiology and Immunology, Medical School

Professor and Veterinarian, Laboratory Animal Medicine; Professor of Learning Health Sciences, Medical School

Denise Kirschner

Professor of Microbiology and Immunology, Medical School

Patrick Schloss

Professor of Microbiology and Immunology, Medical School

Thomas Schmidt

Professor of Internal Medicine - Infectious Diseases, Medical School

Professor of Microbiology and Immunology, Medical School; Professor of Ecology and Evolutionary Biology, College of Literature, Science, and the Arts

David H. Sherman

Professor of Medicinal Chemistry, College of Pharmacy

Professor of Microbiology and Immunology, Medical School; Professor of Chemistry, College of Literature, Science, and the Arts; Research Professor, Life Sciences Institute