Most of my research related to data science involves decision making around clinical trials. In particular, I am interested in how databases of past clinical trial results can inform future trial design and other decisions. Some of my work has involved using machine learning and mathematical optimization to design new combination therapies for cancer based on the results of past trials. Other work has used network meta-analysis to combine the results of randomized controlled trials (RCTs) to better summarize what is currently known about a disease, to design further trials that would be maximally informative, and to study the quality of the control arms used in Phase III trials (which are used for drug approvals). Other work combines toxicity data from clinical trials with toxicity data from other data sources (claims data and adverse event reporting databases) to accelerate detection of adverse drug reactions to newly approved drugs. Lastly, some of my work uses Bayesian inference to accelerate clinical trials with multiple endpoints, learning the link between different endpoints using past clinical trial results.
My research explores the interplay between corporate decisions and employee actions. I currently use anonymized mobile device data to observe individual behaviors, and employ both unsupervised and supervised machine learning techniques.
He develops and applies operations research, data science, and systems approaches to public and private service industries. His research focuses on the management and policy analysis of emerging networked industries and innovative mobility services such as smart parking, connected vehicles, autonomous vehicles, ride-hailing, bike sharing, and car sharing. He has worked extensively with both public and private sector partners worldwide. He is a queueing theorist that uses statistics, stochastic modeling, simulation and dynamic optimization.
My research is at the intersection of Science of Science + Sociology of Organizations + Computational Social Science. I study how social and organizational factors affect scientific discovery. I am especially interested in evaluation practices in science, and whether they promote or stifle innovation. My approach relies primarily on field experiments — interventions in scientific competitions and other settings — and applying computational tools to large-scale observational data.
Current research projects include:
1. Cumulative advantage in science: Do metrics like citation counts and impact factors proxy quality and influence, or help create them?
2. Biases in expert evaluation: Do groups of experts make decisions differently from individuals?
3. Science and the media: What research is picked up by the media, and how is it covered?
Showing how often a paper has been cited causes scientists to perceive it as of lower quality, unless that paper is among the 10% most highly cited.
I am interested in how governance, communities, and inequality emerge in sociotechnical systems, and how the structure of sociotechnical systems encodes and reinforces these processes. To those ends, I develop empirical data and computational methods, focusing on latent variable models; statistical inference in networks; empirical design to study governance in organizations, platforms, and computational social systems; and causal inference and measurement in observational data.
Several sample projects:
> developing empirical populations of networks to infer social and ecological processes encoded in networks
> using probabilistic methods to infer the structure and dynamics of the illicit wildlife trade
> building from theory from political science, statistics, and education to disentangle issues of “bias” in computational systems
Efficient, low regret contextual multi-armed bandit approaches for real time learning including Thompson sampling, UCB, and knowledge gradient descent. Integration of optimization and predictive analytics for determining the time to next measurement, which modality to use, and the optimal control of risk factors to manage chronic disease. Integration of soft voting ensemble classifiers and multiple models Kalman filters for disease state prediction, Real-time (online) contextual multi-armed bandits integrated with optimization of hospital bed type dynamic control decisions for reducing 30-day readmission rates in hospitals. Robustness in system optimization when the system model is uncertain with emphasis on quantile regression forests, sample average approximation, robust optimization and distributionally robust optimization. Health care delivery systems models with prediction and control for inpatient and outpatient. Work has been done on Emergency Department redesign for improved patient flow; Capacity management and planning and scheduling for outpatient care, including integrated services networks; admission control with machine learning to ICUs, stepdown, and regular care units Surgical planning and scheduling for access delay control; Planning and scheduling for Clinical Research Units.
S. Sriram, PhD, is Professor of Marketing in the University of Michigan Ross School of Business, Ann Arbor.
Prof. Sriram’s research interests are in the areas of brand and product portfolio management, multi-sided platforms, healthcare policy, and online education. His research uses state of the art econometric methods to answer important managerial and policy-relevant questions. He has studied topics such as measuring and tracking brand equity and optimal allocation of resources to maintain long-term brand profitability, cannibalization, consumer adoption of technology products, and strategies for multi-sided platforms. Substantively, his research has spanned several industries including consumer packaged goods, technology products and services, retailing, news media, the interface of healthcare and marketing, and MOOCs.
My research focuses on the intended and unintended consequences of language in financial markets. I examine this relationship across a number of contexts, such as the Federal Reserve, initial public offerings, and mergers and acquisitions. More broadly, my work aims to develop new theoretical and methodological approaches to understand the role of language in society.
Professor Seiford’s research interests are primarily in the areas of quality engineering, productivity analysis, process improvement, multiple-criteria decision making, and performance measurement. In addition, he is recognized as one of the world’s experts in the methodology of Data Envelopment Analysis. His current research involves the development of benchmarking models for identifying best-practice in manufacturing and service systems. He has written and co-authored four books and over one hundred articles in the areas of quality, productivity, operations management, process improvement, decision analysis, and decision support systems.
Edward G. Happ is an Executive Fellow at the University of Michigan School of Information, where he is teaching and conducting research. He is also the Co-Founder and former Chairman of NetHope (www.nethope.org), a U.S. based consortium of 50+ leading international relief, development and conservation nonprofits focused on information and communications technology (ICT) and collaboration.