August 10, 2017; Palmer Commons, Great Lakes Central Room

Please join us for the Single-cell Genomic Data Analytics Symposium. The day long symposium will highlight U-M researchers whose work is on the leading edge of innovation and discovery. This symposium is organized by the Michigan Center for Single-Cell Genomic Data Analytics and sponsored by the Michigan Institute for Data Science.


Please register before July 26.

Symposium Schedule

8:00 – 8:45 a.m.              Coffee & Light Breakfast

8:45 – 9:00 a.m.              Welcome Remarks

Alfred Hero, PhD, John H. Holland Distinguished University Professor of Electrical Engineering and Computer Science, R. Jamison and Betty Williams Professor of Engineering, Co-Director for the Michigan Institute for Data Science (MIDAS) , Professor of Biomedical Engineering, Professor of Statistics

9:00 – 10:10 a.m.            Data Analytics I

Joshua Welch, PhD, Postdoctoral Fellow, Broad Institute
‘Matching Single Cell Profiles Across Measurement Types, Conditions, and Biological Replicates’

Yuanfang Guan, PhD, Assistant Professor of Computational Medicine & Bioinformatics, Assistant Professor of Internal Medicine
‘Predicting Isoform Function through Integrating RNA-seq Datasets’

Jun Li, PhD, Associate Professor of Human Genetics, Associate Professor & Associate Chair for Research in Computational Medicine and Bioinformatics
‘Clustering with Sparse Data: The Case of Single-Cell Genomic Profiles’

10:30 – 11:50 a.m.           Biomedical Applications and Study Design

Sue Hammoud, PhD, Assistant Professor of Human Genetics, Assistant Professor of Obstetrics and Gynecology
‘Unraveling the Molecular Program of Spermatogenesis’

Max Wicha, MD, Madeline and Sidney Forbes Professor of Oncology, Director, Forbes Institute for Cancer Discovery, Founding Director Emeritus, University of Michigan Comprehensive Cancer Center
‘Deciphering Tumor Cell Heterogeneity at Single Cell Resolution’

Justin Colacino, PhD, Assistant Professor of Environmental Health Sciences, Assistant Professor of Nutritional Sciences
‘Single Cell Analyses: The Environment and the Developmental Origins of Disease’

Johann Gagnon-Bartsch, PhD, Assistant Professor of Statistics
‘Removing Unwanted Variation with Negative Controls and Replicates’

11:50 – 1:00 p.m.              Box Lunch & Networking

1:00 – 2:00 p.m.                Biomedical Applications: Lightning Talks

Sami Malek, MD, Associate Professor of Hematology, Associate Professor of Medical Oncology
‘Identifying the Cellular Source of Relapse in AML’

Jiandie Lin, PhD, Bradley M. Patten Collegiate Professor in the Life Sciences
‘Elucidating the Landscape of Liver Cell Heterogeneity in Normal and Insulin Resistant States’

Dawen Cai, PhD, Assistant Professor of Cell & Developmental Biology
‘A Single Cell Perspective of Neuronal Subtype and Lineage Mapping in the Drosophila Brain’

Carey Lumeng, MD, PhD, Associate Professor of Internal Medicine – Pediatrics & Communicable Diseases, Associate Professor of Molecular & Integrative Physiology
‘Adipose Tissue Stromal Cells and Obesity’

Edgar Otto, PhD, Research Assistant Professor of Internal Medicine – Nephrology
‘Defining Cellular Heterogeneity in Renal Development and Disease in Multi-center Research Networks’

2:00 – 2:15 p.m.                Coffee Break

2:15 – 3:15 p.m.                Data Analytics II

Xiang Zhou, PhD, Assistant Professor of Biostatistics
‘Nonparametric Bayesian Clustering Analysis for Single-cell RNA Sequencing Data’

Clay Scott, PhD, Associate Professor of Electrical Engineering and Computer Science
Laura Balzano, PhD, Assistant Professor of Electrical Engineering and Computer Science
‘Joint Analysis of Single-cell and Bulk RNA-seq Data via Matrix Factorization’

Anna Gilbert, PhD, Herman H Goldstine Collegiate Professor of Mathematics, Professor of Electrical and Computer Engineering
‘Identifying Genetic Markers: Feature Identification for Sparse Data’

3:15 – 3:30 p.m.                Coffee Break

3:30 – 4:20 p.m.                Resources & Wrap-up

Sunitha Nagrath, PhD, Associate Professor of Chemical Engineering
‘Single Cell Analysis Core of the Comprehensive Cancer Center’

Robert Lyons, PhD, Director of the DNA Sequencing Core
‘UM DNA Sequencing Core: Single-cell Analysis Capabilities’

Coffee, Closing Remarks & Discussion