Applications: Adolescents and Children, Mental Health, Social Sciences, Substance Abuse Methodologies: Causal Inference, Dynamic Treatment Regimes

Daniel Almirall

Assistant Professor, Survey Research Center for Social Research

Daniel Almirall, Ph.D., is Assistant Professor in the Survey Research Center and Faculty Associate in the Population Studies Center in the Institute for Social Research at the University of Michigan.

Prof. Almirall’s current methodological research interests lie in the broad area of causal inference. He is particularly interested in methods for causal inference using longitudinal data sets in which treatments, covariates, and outcomes are all time-varying. He is also interested in developing statistical methods that can be used to form adaptive interventions, sometimes known as dynamic treatment regimes. An adaptive intervention is a sequence of individually tailored decisions rules that specify whether, how, and when to alter the intensity, type, or delivery of treatment at critical decision points in the medical care process. Adaptive interventions are particularly well-suited for the management of chronic diseases, but can be used in any clinical setting in which sequential medical decision making is essential for the welfare of the patient. They hold the promise of enhancing clinical practice by flexibly tailoring treatments to patients when they need it most, and in the most appropriate dose, thereby improving the efficacy and effectiveness of treatment.

Study Design Interests: In addition to developing new statistical methodologies, Prof. Almirall devotes a portion of his research to the design of sequential multiple assignment randomized trials (SMARTs). SMARTs are randomized trial designs that give rise to high-quality data that can be used to develop and optimize adaptive interventions.

Substantive Interests: As an investigator and methodologist in the Institute for Social Research, Prof. Almirall takes part in research in a wide variety of areas of social science and treatment (or interventions) research. He is particularly interested in the substantive areas of mental health (depression, anxiety) and substance abuse, especially as related to children and adolescents.